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Results showed significant reductions in risk of transmission: 75 % (symptomatic HSV-2 acquisition), 50 % (HSV-2 seroconversion), and 48 % (overall HSV-2 acquisition) for valaciclovir compared to placebo. It teaches the principles of applied economic and social statistics in a historical context. Never use any remedy without telling your doctor if you going to become pregnant soon.
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It should be noted that oligohydramnios may not appear until after the fetus has sustained irreversible injury.